Tablet Splitting Performance Evaluation of Losartan Potassium and Olmesartan Medoxomil IR Tablets Marketed in Bangladesh
نویسندگان
چکیده
منابع مشابه
Benicar (olmesartan medoxomil) tablets label
• Nursing mothers: Choose to discontinue nursing or drug (8.3). • In patients with an activated renin-angiotensin system, such as volumeor salt-depletion, renin-angiotensin-aldosterone system (RAAS) blockers such as olmesartan medoxomil can cause excessive hypotension. In susceptible patients, e.g., with renal artery stenosis, RAAS blockers can cause renal failure (5.2, 5.3). • Geriatrics: No o...
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Objective: The objective of the present study was to formulate a controlled release floating tablet of Olmesartan Medoxomil. Methods: Floating tablets of Olmesartan Medoxomil were prepared by direct compression method using both natural (sodium alginate and carrageenan) and semi synthetic polymers (HPMC K4M, HPMC K100LV and HPMC E50LV).Sodium bicarbonate and calcium carbonate were used as gas g...
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A simultaneous determination of olmesartan medoxomil and hydrochlorothiazide by absorption ratio spectrophotometric method has been developed in combined tablet dosage form. The method is based on measurements of absorbance at isoabsoptive point. The Beer's law obeys in the range of 10-30 mug/ml for both olmesartan medoxomil and hydrochlorothiazide respectively. The proposed method was validate...
متن کاملMouth Dissolving Tablets of Losartan Potassium: Formulation and Evaluation
Losartan potassium is an angiotention receptor antagonist, used in the management of hypertension. The objective of the proposed research work is to prepare and evaluate the mouth dissolving/disintegrating tablets (MDTs) of losartan Potassium, which avoid the first-pass metabolism, improved the dissolution rate and enhance the bioavailability. Mouth dissolving tablets (MDTs) were prepared by di...
متن کاملPreparation, Characterization and Evaluation of Olmesartan Medoxomil-β Cyclodextrin Complexes
Olmesartan medoxomil is a poor water soluble drug. There are numerous approaches available and reported in literature to enhance the solubility of poor water soluble drugs among which cyclodextrin complexation is predominant. β-cyclodextrin was used since this possess a special ability to complex with drugs enabling them to increase solubility, reduce bitterness, enhance stability and decrease ...
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ژورنال
عنوان ژورنال: Bangladesh Pharmaceutical Journal
سال: 2020
ISSN: 2408-8463,0301-4606
DOI: 10.3329/bpj.v23i2.48335